Emotional disorders in adolescence II - from the perspective of a clinical psychologistCase report

PhDr. Veronika Buchtová

Psychiatr. praxi. 2025;26(3):197-201 | DOI: 10.36290/psy.2025.032

In psychiatric practice behavioral and emotional disorders are relatively often diagnosed in adolescent girls. We present the differential diagnosis of behavioral and emotional disorders in early adolescence in disharmoniously developing patient and treatment plan (based on consideration of personality, social, and up-bringing precursors of difficulties).

The patient from the perspective of selected criminal law and criminological issuesLaw in psychiatry

JUDr. Petr Jambor

Psychiatr. praxi. 2025;26(3):189-196 | DOI: 10.36290/psy.2025.031

Healthcare providers may come into contact with people who are victims and sometimes perpetrators of crime as part of their professional activities. This article deals with the powers and duties of healthcare providers towards patients who are victims or perpetrators of crime. It also looks at how healthcare professionals can protect themselves from threats from patients. Early detection and identification of patient victimization is a difficult task, especially when the victim is particularly vulnerable, the victim of a very hurtful (sensitive) crime. In this context, we therefore also refer to the issue of domestic violence, the CAN syndrome, and...

The impact of opioids and substitution treatment on cognitive functionsReview articles

Mgr. Aneta Votavová, Mgr. Lenka Šťastná, Ph.D.

Psychiatr. praxi. 2025;26(3):184-188 | DOI: 10.36290/psy.2025.030

This theoretical article focuses on the relationship between opiates and cognitive functions, which can lead to significant changes ranging from acute effects to long-term deficits. Published studies indicate impaired cognitive functions, with some difficulties persisting even during abstinence. Prenatal opioid exposure is associated with high risks for child development, underscoring the importance of prevention and support for pregnant users. Although substitution treatment reduces the incidence of relapse, it may continue to negatively affect cognitive status. Contradictory research findings stem from various factors, such as differing methodologies,...

Integrating music therapy into schema therapy for hospitalized patients with mental disorders: Clinical reflections and case examplesReview articles

Mgr. et Mgr. Zdeněk Maté, prof. MUDr. Ján Praško, CSc., Mgr. Draga Čermáková, PhDr. Marie Ocisková, Ph.D.

Psychiatr. praxi. 2025;26(3):172-180 | DOI: 10.36290/psy.2025.029

Background: This article explores the integration of music therapy techniques into schema therapy for hospitalized patients with various psychiatric diagnoses. The aim is to examine how music can support experiential work, schema processing, and the activation of healthy modes. Methods: A case-based approach is used to present four hospitalized patients with depression, bipolar disorder, schizophrenia, and social anxiety. Each case includes short conceptualization and description of music therapy interventions within the schema therapy framework. Results: The integration of music therapy facilitated emotional expression and awareness, reduced internal...

The increasing rate of suicidal behavior in preadolescent children after COVID-19 pandemic. The profile of suicidal children hospitalized in department of children psychiatryReview articles

MUDr. Katarína Jaššová, Ph.D., MUDr. Markéta Holá, MUDr. Tereza Podhorná

Psychiatr. praxi. 2025;26(3):168-171 | DOI: 10.36290/psy.2025.028

The rate of suicidality in children has been rising rapidly in recent years. While the issue of suicidal behavior in adolescents is explored relatively well, suicidality in preadolescents remains slightly underreported. The team of authors examined the increasing rate of suicidal behavior among children as an indication for hospitalization in the Department of Child Psychiatry of the FTN. Compared to 2019, in 2022 we recorded an almost 3-times growth in hospitalized children for suicidal behavior and a 5-times growth in hospitalizations for suicide attempts. The most common risk factor for suicidal children is premorbid psychiatric comorbidity and...

Transgender identity and mental healthReview articles

MUDr. Daniela Kestlerová

Psychiatr. praxi. 2025;26(3):164-166 | DOI: 10.36290/psy.2025.027

This review article aims to provide an overview of the current state of knowledge in the field of transgender identity and mental health, identify major challenges, and suggest directions for future research and interventions. In the following sections of the article, we will focus on analyzing the literature on the mental health of transgender individuals, paying particular attention to factors that contribute to both mental well-being and distress. Next, we will look at strategies and interventions that can support the mental health of this population, with an emphasis on an informed approach in health and community services.

The phenomenon of nonsuicidal self-injury - how can we help effectively? - Part 2: Guiding and accompanying our patients towards recoveryReview articles

MUDr. Michaela Chmelíková

Psychiatr. praxi. 2025;26(3):156-163 | DOI: 10.36290/psy.2025.026

This section of the text is dedicated to the principles of effective approaches to individuals who self-harm and to the available treatment options (psychotherapy, pharmacotherapy), as recently recommended in the professional literature and as they have proven effective in psychiatric and psychotherapeutic practice. It places particular emphasis on the practical applicability of the presented knowledge in everyday outpatient psychiatric settings. Therefore, it focuses especially on interventions or educational resources that can be directly offered or recommended to patients, their families, or close ones within time-limited conditions. As an example...

Pharmacokinetic aspects of the second generation long acting injectable antipsychoticsReview articles

MUDr. Martin Hýža, Ph.D., MUDr. Tomáš Skřont

Psychiatr. praxi. 2025;26(3):151-155 | DOI: 10.36290/psy.2025.025

Second generation long acting injectable antipsychotics supply gradually the portfolio of the agents available for the treatment of schizophrenia. The first preparation (risperidon microspheres) has been approved by FDA already in 2003, the last one (aripiprazol monohydrate once in two months) even in the last year. Compared to the first generation their great advantage is in better tolerability and the potential to improve affective symptoms among others. Recently new preparations with longer interval (2 or 3 months) have been introduced. Second generation LAI antipsychotics are characterized with more precisely defined pharmacokinetic profiles and...

The diagnosis and pharmacotherapy of adult ADHD - part 2Review articles

MUDr. Michal Vodička

Psychiatr. praxi. 2025;26(3):143-150 | DOI: 10.36290/psy.2025.024

The second part of the review article on ADHD focuses on the common comorbid disorders that co-occur with ADHD, their differential diagnosis and current pharmacotherapeutic approaches targeting ADHD and individual comorbidities. Furthermore, it addresses the issue of self-injurious and suicidal behaviours in patients with ADHD, along with pharmacological interventions for these conditions.

Pište také pro nás!Editorial

MUDr. Radkin Honzák, CSc.

Psychiatr. praxi. 2025;26(2):67  

Léčba hypomagnezemie jako možné příčiny některých symptomů neurologických poruchCommercial presentation

MUDr. Jiří Havel, MSc.

Psychiatr. praxi. 2025;26(2):130-134  

Highligths: informace a dojmy z 10. mezinárodního sympozia Světové federace ADHDHeard at a congress

MUDr. Hedvika Ernsten

Psychiatr. praxi. 2025;26(2):127-129  

Comorbid anorexia nervosa and obsessive-compulsive disorder in adolescence - a case reportCase report

MUDr. Barbora Pilátová, MUDr. Kryštof Kantor, Ph.D., doc. PhDr. Jana Kocourková

Psychiatr. praxi. 2025;26(2):123-126 | DOI: 10.36290/psy.2025.021  

Anorexia nervosa and obsessive-compulsive disorder (OCD) are mental disorders that often develop during adolescence. These conditions share some common features and can occur simultaneously, which can lead to complications in the diagnosis and treatment of both disorders. Adolescence is a specific period of life that is associated with rapid changes in psychological status, even in the absence of pathology. In the case study of an adolescent girl, we highlight the phenomenological overlap in symptomatology between these two comorbid disorders and the fact that correct differentiation of the causes of the observed behaviours can play an important role...

Altered pharmacokinetics of selected psychopharmaceuticals in patients with chronic kidney diseaseReview articles

Mgr. Michaela Jelínková, PharmDr. Jan Miroslav Hartinger, Ph.D.

Psychiatr. praxi. 2025;26(2):116-122 | DOI: 10.36290/psy.2025.020  

Psychiatric illness and delirious states treated with psychopharmaceuticals are common comorbidities in patients with renal impairment. Although the conventional wisdom is that most psychopharmaceuticals are lipophilic in nature and are not renally eliminated, this is not true for a number of commonly administered drugs, and their dosing needs to be adjusted in patients with chronic kidney disease (CKD) or acute kidney injury (AKI). The present article focuses on the effect of impaired renal function and extracorporeal elimination methods on renally eliminated psychopharmaceuticals, especially thiapride, amisulpride, sulpiride, risperidone, paliperidone,...

The diagnosis and pharmacotherapy of Adult ADHD - part 1Review articles

MUDr. Michal Vodička

Psychiatr. praxi. 2025;26(2):108-115 | DOI: 10.36290/psy.2025.019  

The introductory part of this review article on ADHD presents the prevalence, historical development, etiology, symptoms and diagnosis, including the importance of psychological assessment. It also discusses the pharmacotherapeutic options available in the Czech Republic, including their efficacy, side effects, interactions with other medications, potential health risks, and specific aspects of use in pregnancy and lactation. It also describes the differences between ADHD in childhood and adulthood.

Internet psychoeducation and psychotherapy for obsessive-compulsive disorder - reviewReview articles

MUDr. Jan Pásztor, prof. MUDr. Ján Praško, Ph.D., MUDr. Jakub Vaněk, Ph.D., MUDr. Jozef Višňovský, doc. PhDr. PaedDr. Marta Zaťková, PhD., PhDr. Miloš Šlepecký, CSc., prof. PhDr. Tomáš Sollár, PhD., MUDr. Vlastimil Nesnídal

Psychiatr. praxi. 2025;26(2):101-106 | DOI: 10.36290/psy.2025.018  

Objective: The aim of this review article is to describe the effectiveness and accessibility of internet-based psychoeducation and psychotherapy for obsessive-compulsive disorder (OCD). The focus is on various forms of internet therapy, including cognitive behavioral therapy (CBT), acceptance and commitment therapy (ACT), and mindfulness techniques. Methods: Relevant studies published between 2010 and 2024 were selected for this review. Randomized controlled trials, meta-analyses, and systematic reviews evaluating the effectiveness of internet-based psychoeducation and psychotherapy for patients with OCD were included. Data were analyzed for effectiveness,...

The phenomenon of nonsuicidal self-injury - how can we help effectively? Part 1: Understanding nonsuicidal self-injury as a symptomReview articles

MUDr. Michaela Chmelíková

Psychiatr. praxi. 2025;26(2):94-100 | DOI: 10.36290/psy.2025.017  

This article first explores the theoretical framework of nonsuicidal self-injury (NSSI) (definition, classification, epidemiology, etiological factors) and then presents current findings on the behavioral manifestations of self-injurious behavior. Special emphasis is placed on conveying an understanding of the subjective experiences and needs of individuals suffering from this symptom. Understanding is shown to be a crucial factor in shaping an appropriate professional approach to the issue. The topic of NSSI is burdened by numerous myths and stigmatizing prejudices, which can either directly discourage affected individuals from seeking professional...

The effect of transcranial magnetic stimulation on cognitive functions in patients with depressionReview articles

Mgr. Markéta Kubinová, doc. MUDr. Lucie Kališová, Ph.D.

Psychiatr. praxi. 2025;26(2):88-92 | DOI: 10.36290/psy.2025.016  

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive biological treatment method in many psychiatric, neurological, and otolaryngological indications. In psychiatry, rTMS proved its treatment effect mainly in the treatment of depression. rTMS is a well-tolerated treatment method, and side effects occur with proper indication and preparation rarely. This review brings comprehensive information about the impact of rTMS on cognitive performance in patients with depression. Results conclude that rTMS does not impair cognitive functions and, on the other hand, has a potential for improvement of cognition. This article confirms the safety...

Treatment of pharmacoresistant states in psychiatry. Part 2: Treatment-resistant depressionReview articles

prof. MUDr. Eva Češková, CSc.

Psychiatr. praxi. 2025;26(2):83-86 | DOI: 10.36290/psy.2025.015  

The paper is focused on pharmacotherapy of treatment-resistant depression and presents the treatment possibilities, e.g. switch to another antidepressant, augmentation and combination of antidepressants. In more details the augmentation with the first (ketamine, esketamine) and the second generation (esmethadone) of uncompetitive NMDA receptors antagonists, so called rapid acting antidepressants is described. Further, there are mentioned some substances used before psychopharmacological era (opioids, psilocybin) and alternative approaches (nutraceuticals, probiotics), which have certain potential to reduce severe depressive symptoms.

Generalized anxiety disorder and its treatmentReview articles

MUDr. Katarína Adamcová, MUDr. Pavla Stopková, Ph.D., Mgr. Markéta Jablonská, Mgr. David Jakeš, Barbora Darmová, Mgr. et Mgr. Iveta Fajnerová, Ph.D.

Psychiatr. praxi. 2025;26(2):75-82 | DOI: 10.36290/psy.2025.014  

Generalized Anxiety Disorder (GAD) is characterized by chronic and excessive worries across various aspects of daily life, including personal and work-related responsibilities, health, and interpersonal relationships. The diagnostic criteria undergo a slight modification with the transition from the 10th edition of the International classification of diseases (ICD-10) to the new version, ICD-11. This article examines the changes in the new classification, which is expected to become the diagnostic guideline in the coming years. The aim of this article is to explore in detail the characteristics of generalized anxiety disorder, its diagnostic challenges,...

Pharmacokinetic aspects of the treatment with long-acting injectable antipsychotics and specific features of the first generation preparationsReview articles

MUDr. Martin Hýža, Ph.D., MUDr. Tomáš Skřont

Psychiatr. praxi. 2025;26(2):71-74 | DOI: 10.36290/psy.2025.013  

Long acting injectable antipsychotics overcome few troubles related to long term treatment of patients with schizophrenia, especially the frequent non-adherence. They are used in the treatment of schizophrenia for almost 60 years. Compared to per os drug forms, the principles of pharmacokinetics are different. Its dynamics is led by the amount of a drug released from the site of application. Using the simple conversion of equivalent dose is burdened with a risk of plasma level decline and resulting increased risk of relapse; to overcome this, using of per os supplementation or loading patterns is recommended. The use of TDM is advantageous during switch...

Farmakoterapie schizofrenie při komorbidním abúzu. Využití kariprazinu v klinické praxiHeard at a congress

MUDr. Zuzana Zafarová

Psychiatr. praxi. 2025;26(1):55-62  

Můžeme léčit schizofrenii tak, aby byl spokojený lékař i pacient?Heard at a congress

MUDr. Zuzana Zafarová

Psychiatr. praxi. 2025;26(1):48-54  

Loss of voice as a rare side effect of long-term lithium treatment: A case study of a 32-year-old patient with bipolar affective disorderCase report

MUDr. Eliška Nádvorníková

Psychiatr. praxi. 2025;26(1):46-47 | DOI: 10.36290/psy.2025.009  

This case study describes a 32-year-old woman suffering from bipolar affective disorder who was hospitalized in the psychiatric department of CNS Center Třinec due to a voice loss lasting 10 months. The patient had been under psychiatric care since 2013, when she was admitted to the unit shortly after the birth of her daughter, presenting with psychotic symptoms. In 2014, she exhibited signs of a manic episode, necessitating hospitalization and the initiation of lithium as a mood stabilizer. In 2023, following a thorough somatic examination due to the prolonged voice loss, an organic cause for her difficulties was ruled out. Based on the assessment,...

Case study of a patient with Wernicke's encephalopathy caused by excessive dietCase report

Šimon Pisko, prof. MUDr. Bc. Libor Ustohal, Ph.D.

Psychiatr. praxi. 2025;26(1):43-45 | DOI: 10.36290/psy.2025.008  

The patient was admitted to the Department of Psychiatry of Masaryk University and University Hospital Brno with a diagnosis of a delirious state not superimposed on dementia. Based on a more detailed medical history and another assessment, the cause of this state and of the duration of some symptoms was determined as Wernicke's encephalopathy. Treatment was adjusted accordingly using thiamine, which led to further improvement of the patient's condition. Due to persistent ataxia, the patient was subsequently transferred to the neurology rehabilitation department.

Effectiveness of treatment in a psychotherapeutic ward for patients with borderline personality disorder: pilot studyOriginal articles

MUDr. Jan Pásztor, prof. MUDr. Ján Praško, CSc., PhDr. Marie Ocisková, Ph.D., Ing. Mgr. Marina Jermářová, Mgr. Karolína Richtrová, MUDr. David Pánek, Ph.D., Mgr. Draga Čermáková, Mgr. et Mgr. Zdeněk Maté, MUDr. Pavel Doubek, Ph.D., MUDr. Martin Hollý

Psychiatr. praxi. 2025;26(1):36-42 | DOI: 10.36290/psy.2025.007  

Objective: This study aimed to assess the effectiveness of a six-week therapeutic program combining elements of schema therapy and cognitive-behavioral therapy (CBT) for patients with borderline personality disorder (BPD). Method: The study included 51 patients diagnosed with BPD who participated in the program between January and September 2024. Treatment effectiveness was evaluated using several self-report measures: Borderline Symptom List 23 (BSL-23), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7) and Positive Self-Relation Scale (PSRS). Trained psychologists administered a rating scale Clinical Global Impression...

Self-compassion - A cure for anxiety?Review articles

Ing. Marek Vich, Ph.D.

Psychiatr. praxi. 2025;26(1):30-35 | DOI: 10.36290/psy.2025.006  

Anxiety disorders are currently the most common group of mental disorders, affecting more than 300 million people worldwide. Budgets for the treatment and prevention of these disorders are very limited. The article focuses on self-compassion, which is an available approach to reducing anxiety symptoms as well as potentially treating anxiety disorders. The above text is mainly based on the theory of three systems of emotion regulation, as well as studies focusing on the relationship between self-compassion, anxiety symptoms, emotional attachment and oxytocin. Based on this, recommendations for future studies are presented. For the future development...

Music therapy for children with autism spectrum disordersReview articles

PhDr. Markéta Gerlichová, Ph.D., prof. Dr. Dr. Dr. Dr. Wolfgang Mastnak, MUDr. Martin Kučera

Psychiatr. praxi. 2025;26(1):25-29 | DOI: 10.36290/psy.2025.005  

The aim of the article is to broaden the awareness of the field of music therapy and the possibilities of applying music therapy approaches, methods and techniques to children with autism spectrum disorder (ASD). It covers the development of scientific knowledge including current findings from research and practice. The article concludes with specific music therapy exercises.

Pharmacogenetic testing in hospitalized psychiatric patients: benefits and interpretation importanceReview articles

PharmDr. Ivana Tašková, Ph.D., Mgr. Nicole Šafářová

Psychiatr. praxi. 2025;26(1):19-24 | DOI: 10.36290/psy.2025.004  

Our article aims to introduce the reader to pharmacogenetic (PGx) testing in psychiatry, where it currently represents an available and significant tool in personalized medicine. PGx testing enables the adjustment of pharmacotherapy based on patients' genetic predispositions. In psychiatry, PGx testing focuses on polymorphisms in genes responsible for drug metabolism, primarily cytochrome P450 enzymes such as CYP2C19 and CYP2D6. In clinical practice, these tests can help predict drug efficacy or toxicity, thereby improving the safety and effectiveness of pharmacotherapy. PGx testing, which was conducted at the Bohnice Psychiatric Hospital, was done...

The psychiatry of transgender identityReview articles

doc. MUDr. Luděk Fiala, Ph.D., MBA

Psychiatr. praxi. 2025;26(1):16-18 | DOI: 10.36290/psy.2025.003  

This review article addresses not only historical but also contemporary approaches to the significant medical problem of transsexuality. It examines the psychiatric processes associated with transsexuality, as well as changes in diagnostic classifications and the evolution of affirmative care practices. The role of psychiatry in the transition process is explored, along with the controversies surrounding the diagnosis of gender dysphoria. It also focuses on the relationship between transgender people and health care. The article aims to present modern perspectives and trends that support the transgender community and advocate for the depathologization...