Internet-based CBT for generalized anxiety: a pilot studyCase report#E-version

MUDr. Kamila Bělohradová, prof. MUDr. Ján Praško, CSc., PhDr. Marie Ocisková, Ph.D., MUDr. Jan Pásztor, MUDr. Kryštof Kantor, Ph.D., Mgr. et Mgr. Zdeněk Maté, MUDr. Vlastimil Nesnídal, MUDr. Kristýna Vrbová, Ph.D., MUDr. František Vlček, Ph.D., MHA, David Kwolek, Ing. Jelena Holomany, MSc.

Psychiatr. praxi. 2026;27(1):E1-E7 | DOI: 10.36290/psy.2026.009

Background: Generalized Anxiety Disorder (GAD) is one of the most prevalent anxiety disorders, significantly affecting patients' quality of life. However, access to traditional psychotherapy is often hindered by stigma and geographical or financial barriers. Internet-based therapeutic programs, such as Mindwell, offer an accessible alternative based on Cognitive Behavioral Therapy (CBT) principles. Objective: This study aimed to evaluate the effectiveness and adherence of the internet-based psychoeducational program Mindwell in individuals with mild to moderate symptoms of GAD. Method: A total of 209 patients were enrolled in the program based on recommendations...

Svět kolem nás se měníEditorial

MUDr. Jan Hálek, Ph.D.

Psychiatr. praxi. 2026;27(1):3

Zaznělo na 68. česko-slovenské psychofarmakologické konferenci ve dnech 14.-18. ledna 2026 v Mariánských LázníchSympozium společnosti Angelini Pharma: Na pomalých vlnách farmakologické ukolébavkyHeard at a congress

Redakce

Psychiatr. praxi. 2026;27(1):63-66

Jak pomoci adolescentům s ADHDHeard at a congress

Redakce

Psychiatr. praxi. 2026;27(1):60-62

On-line romance scamCase report

MUDr. Jakub Šimon

Psychiatr. praxi. 2026;27(1):52-59 | DOI: 10.36290/psy.2026.008

The article examines a hidden, and serious phenomenon that has devastating psychological, social, and financial impacts. It is a relatively new type of crime that deliberately targets the fundamental human need for love and connection. The article debunks common misconceptions about the profile of victims. It explains the techniques of psychological manipulation, such as love bombing, mirroring, and the creation of a trauma bond. Through two case studies, it demonstrates how psychological manipulation and trauma manifest in the clinical presentation of victims. It addresses the challenges of differential diagnosis and argues that the seemingly delusional...

Risks of valproate treatment in elderly patients with hypoalbuminemia - the importance of therapeutic dose measurement and a case report from gerontopsychiatric practiceCase report

PharmDr. Kateřina Skopalová, Ph.D., doc. MUDr. Mgr. Bc. Jan Lužný, Ph.D.

Psychiatr. praxi. 2026;27(1):49-51 | DOI: 10.36290/psy.2026.007

In current gerontopsychiatric practice, it is customary to determine the levels of total valproate through therapeutic level measurement (TDM), but it is also important to determine the levels of albumin and especially the free fraction of valproate in a specific patient. It is the free fraction of valproate (i. e. the biologically active part of the drug that is not bound to albumin) that determines not only its pharmacodynamic activity, but also the adverse effects or even toxicity of valproate. Hypoalbuminemia is a very common finding in older patients, which also leads to an increase in the free (not bound to albumin) fraction of valproate even...

Early dose escalation of lurasidone as part of combination pharmacotherapy in a patient with schizophreniaCase report

MUDr. Adam Nemček, PhD.

Psychiatr. praxi. 2026;27(1):44-48 | DOI: 10.36290/psy.2026.010

Inadequate response to initial antipsychotic therapy is relatively common in patients with schizophrenia. In case of inadequate response to initial antipsychotic treatment, it is possible to increase the dose of initial antipsychotic, replace the antipsychotic with another, or resort to a combination of antipsychotics. Insufficient response to antipsychotic treatment after two weeks is a negative predictor of response to the aforementioned treatment even in the longer term. Therefore, the period of two weeks from the start of treatment appears to be a suitable interval for assessing the effectiveness of an antipsychotic and also the time for intervention....

Internet-based CBT for depression: a pilot studyOriginal articles

MUDr. Jan Pásztor, prof. MUDr. Ján Praško, CSc., PhDr. Marie Ocisková, Ph.D., MUDr. Vlastimil Nesnídal, MUDr. Kryštof Kantor, MUDr. Kristýna Vrbová, Ph.D., Mgr. et Mgr. Zdeněk Maté, David Kwolek, Anton Sverlov, MUDr. František Vlček, Ph.D., Ing. Jelena Holomany, MSc.

Psychiatr. praxi. 2026;27(1):36-42 | DOI: 10.36290/psy.2026.006

Introduction: Major depressive disorder is one of the most common mental disorders, but many patients do not have access to appropriate psychotherapy due to limited service availability, stigma, or financial barriers. Internet-based cognitive behavioral therapy (CBT)-based therapeutic programs represent an innovative and affordable alternative to standard psychotherapy. This study aims to evaluate the feasibility, adherence, and effectiveness of the Mindwell online CBT program for people with mild to moderate depressive symptoms. Method: A total of 188 patients who were referred by health insurance companies based on referrals from outpatient psychiatrists...

Physical activity in the treatment of schizophreniaReview articles

prof. MUDr. Lucie Bankovská Motlová, Ph.D.

Psychiatr. praxi. 2026;27(1):33-35 | DOI: 10.36290/psy.2026.005

Physical activity should be a routine part of the treatment plan for patients with schizophrenia. Studies have shown a beneficial effect of exercise on cognitive function, positive, negative and depressive symptoms, and improvements in social skills and overall physical fitness. Individual and group programs, lasting at least six months, are optimal, with endurance aerobic training with rhythmic engagement of large muscle groups under the supervision of a trainer, for one hour at least 3 times a week. Exercise is a non-stigmatizing and safe intervention, with a minimum of adverse effects and a maximum of desirable ones.

Ketamine in clinical psychiatry and addictology - a narrative reviewReview articles

MUDr. Ondřej Vašíček, MUDr. Tomáš Páleníček,Ph.D.

Psychiatr. praxi. 2026;27(1):25-32 | DOI: 10.36290/psy.2026.004

Ketamine administered at subanesthetic doses represents a rapidly acting and safe intervention with the most robust evidence for efficacy in major depressive disorder, particularly in treatment-resistant depression. In a subset of patients, a rapid reduction in suicidal ideation has also been observed. The effect of a single administration is typically time-limited and usually necessitates repeated or maintenance dosing within a defined clinical regimen. In clinical practice, off-label use of racemic ketamine is encountered alongside intranasal S-ketamine (Spravato®) used within officially approved indications, whereas R-ketamine remains experimental....

Department for diagnostics and psychoeducation in attention deficit disorders and ADHD in adultsReview articles

MUDr. Tereza Petrásková, Ph.D., prof. MUDr. Ján Praško, CSc., Tereza Příhodová, M.A., Ph.D., Mgr. Veronika Lechovská, PhDr. Marie Ocisková, Ph.D., PhDr. Daniel Jurák, Ph.D., MUDr. David Pánek, Ph.D., Michal Heinzl, Bc. Filip Měchura, Bc. Monika Lukášová, Mgr. Hana Štětková, Bc. Martin Pícl

Psychiatr. praxi. 2026;27(1):17-24 | DOI: 10.36290/psy.2026.003

The article presents the structure and content of a twelve-day inpatient program focused on the diagnostics and psychoeducation of attention deficit disorders in adults. The program takes place at a specialized unit integrating clinical assessments with daily psychoeducational sessions. These sessions aim to enhance patients' understanding of ADHD and other attention disorders, develop coping strategies, and support self-regulation. The program is interdisciplinary, involving collaboration among a psychiatrist, clinical psychologist, neurologist, physiotherapist, somnologist, nutrition and addiction specialist, and music therapist. The article outlines...

Telemedicine in child psychiatry: current situation and future challengesReview articles

MUDr. Šárka Bínová

Psychiatr. praxi. 2026;27(1):12-16 | DOI: 10.36290/psy.2026.002

Telemedicine is a modern method of providing healthcare that uses information and communication technologies to enable remote contact between doctors and patients. Its aim is to improve the availability of specialist care, facilitate long-term patient monitoring, and make more efficient use of healthcare system capacity. In the Czech Republic, child psychiatry was one of the first fields to begin systematically using telemedicine. Since January 2024, remote contact in child psychiatry using video cameras has been officially available, becoming an important addition to outpatient care. This article summarizes two years of clinical experience with the...

Mood stabilisersReview articles

doc. PharmDr. Jana Hroudová, Ph.D., PharmDr. Alena Pilková, Ph.D., doc. MUDr. Lucie Kališová, Ph.D.

Psychiatr. praxi. 2026;27(1):6-11 | DOI: 10.36290/psy.2026.001

This article provides a comprehensive summary of mood stabilizers used in routine clinical psychiatric practice in the Czech Republic. These medications are used to reduce the risk of depressive or manic episodes in patients with bipolar or schizoaffective disorder. The article pays particular attention to lithium, covering its pharmacological profile, proven efficacy, and adverse effects associated with its administration. Additionally, sodium valproate, carbamazepine, and lamotrigine are described in detail from pharmacological and psychiatric perspectives. The article concludes with a summary of recommendations for clinical practice.

The collaboration of music therapy and schema therapy in inpatient psychiatric care of patients with borderline personality disorder: Clinical case studies and practical recommendationsReview articles#E-version

Mgr. et Mgr. Zdeněk Maté, prof. MUDr. Ján Praško, CSc., Mgr. Karolína Richtrová, MUDr. Jan Pasztor, Mgr. Draga Čermáková, Mgr. Marina Jermařová, PhDr. Marie Ocisková, PhD.

Psychiatr. praxi. 2025;26(3):E1-E9 | DOI: 10.36290/psy.2025.034

This article explores the collaboration of music therapy with schema therapy in both group and individual formats. The aim is to examine how music therapy can enhance experiential work in schema therapy, particularly in the context of mode dialogues, managing the Inner Critic, soothing the Vulnerable Child, and developing the Kind Parent. The article focuses on the potential of combining these two approaches and provides practical examples of how music therapy can be incorporated into therapeutic techniques. Reflections from patients with borderline personality disorder (BPD) suggest that this combination can improve emotional access and facilitate...

Ambulantní psychiatrie – základ psychiatrické péčeEditorial

MUDr. Simona Papežová ve spolupráci se Sekcí ambulantní péče Psychiatrické společnosti ČLS JEP

Psychiatr. praxi. 2025;26(3):139-140

Hypomagnezemie jako nejčastější nediagnostikovaná iontová nerovnováha v klinické praxi a jak ji řešitCommercial presentation

MUDr. Jiří Havel, MSc.

Psychiatr. praxi. 2025;26(3):206-210

Exposure and cue-exposure therapy in addiction treatment - discussion of reservationsComments

MUDr. Milan Beniš, MUDr. Jiří Podlipný, Ph.D.

Psychiatr. praxi. 2025;26(3):202-205 | DOI: 10.36290/psy.2025.033

Techniques using exposure in the treatment of mental disorders are widespread, well-known and usually have well-founded effectiveness. In the treatment of addiction, cue-exposure therapy (CET) based on the principle of exposure is mainly used. However, some therapists and experts from the community of people treating substance dependence criticize the use of exposure treatments. Their reservations have the character of ethical considerations, principled contradictions and doubts. These reservations are most often heard in discussions and have the character of an expert opinion. It is also true that reservations cannot be found in publications, or it...

Emotional disorders in adolescence II - from the perspective of a clinical psychologistCase report

PhDr. Veronika Buchtová

Psychiatr. praxi. 2025;26(3):197-201 | DOI: 10.36290/psy.2025.032

In psychiatric practice behavioral and emotional disorders are relatively often diagnosed in adolescent girls. We present the differential diagnosis of behavioral and emotional disorders in early adolescence in disharmoniously developing patient and treatment plan (based on consideration of personality, social, and up-bringing precursors of difficulties).

The patient from the perspective of selected criminal law and criminological issuesLaw in psychiatry

JUDr. Petr Jambor

Psychiatr. praxi. 2025;26(3):189-196 | DOI: 10.36290/psy.2025.031

Healthcare providers may come into contact with people who are victims and sometimes perpetrators of crime as part of their professional activities. This article deals with the powers and duties of healthcare providers towards patients who are victims or perpetrators of crime. It also looks at how healthcare professionals can protect themselves from threats from patients. Early detection and identification of patient victimization is a difficult task, especially when the victim is particularly vulnerable, the victim of a very hurtful (sensitive) crime. In this context, we therefore also refer to the issue of domestic violence, the CAN syndrome, and...

The impact of opioids and substitution treatment on cognitive functionsReview articles

Mgr. Aneta Votavová, Mgr. Lenka Šťastná, Ph.D.

Psychiatr. praxi. 2025;26(3):184-188 | DOI: 10.36290/psy.2025.030

This theoretical article focuses on the relationship between opiates and cognitive functions, which can lead to significant changes ranging from acute effects to long-term deficits. Published studies indicate impaired cognitive functions, with some difficulties persisting even during abstinence. Prenatal opioid exposure is associated with high risks for child development, underscoring the importance of prevention and support for pregnant users. Although substitution treatment reduces the incidence of relapse, it may continue to negatively affect cognitive status. Contradictory research findings stem from various factors, such as differing methodologies,...

Integrating music therapy into schema therapy for hospitalized patients with mental disorders: Clinical reflections and case examplesReview articles

Mgr. et Mgr. Zdeněk Maté, prof. MUDr. Ján Praško, CSc., Mgr. Draga Čermáková, PhDr. Marie Ocisková, Ph.D.

Psychiatr. praxi. 2025;26(3):172-180 | DOI: 10.36290/psy.2025.029

Background: This article explores the integration of music therapy techniques into schema therapy for hospitalized patients with various psychiatric diagnoses. The aim is to examine how music can support experiential work, schema processing, and the activation of healthy modes. Methods: A case-based approach is used to present four hospitalized patients with depression, bipolar disorder, schizophrenia, and social anxiety. Each case includes short conceptualization and description of music therapy interventions within the schema therapy framework. Results: The integration of music therapy facilitated emotional expression and awareness, reduced internal...

The increasing rate of suicidal behavior in preadolescent children after COVID-19 pandemic. The profile of suicidal children hospitalized in department of children psychiatryReview articles

MUDr. Katarína Jaššová, Ph.D., MUDr. Markéta Holá, MUDr. Tereza Podhorná

Psychiatr. praxi. 2025;26(3):168-171 | DOI: 10.36290/psy.2025.028

The rate of suicidality in children has been rising rapidly in recent years. While the issue of suicidal behavior in adolescents is explored relatively well, suicidality in preadolescents remains slightly underreported. The team of authors examined the increasing rate of suicidal behavior among children as an indication for hospitalization in the Department of Child Psychiatry of the FTN. Compared to 2019, in 2022 we recorded an almost 3-times growth in hospitalized children for suicidal behavior and a 5-times growth in hospitalizations for suicide attempts. The most common risk factor for suicidal children is premorbid psychiatric comorbidity and...

Transgender identity and mental healthReview articles

MUDr. Daniela Kestlerová

Psychiatr. praxi. 2025;26(3):164-166 | DOI: 10.36290/psy.2025.027

This review article aims to provide an overview of the current state of knowledge in the field of transgender identity and mental health, identify major challenges, and suggest directions for future research and interventions. In the following sections of the article, we will focus on analyzing the literature on the mental health of transgender individuals, paying particular attention to factors that contribute to both mental well-being and distress. Next, we will look at strategies and interventions that can support the mental health of this population, with an emphasis on an informed approach in health and community services.

The phenomenon of nonsuicidal self-injury - how can we help effectively? - Part 2: Guiding and accompanying our patients towards recoveryReview articles

MUDr. Michaela Chmelíková

Psychiatr. praxi. 2025;26(3):156-163 | DOI: 10.36290/psy.2025.026

This section of the text is dedicated to the principles of effective approaches to individuals who self-harm and to the available treatment options (psychotherapy, pharmacotherapy), as recently recommended in the professional literature and as they have proven effective in psychiatric and psychotherapeutic practice. It places particular emphasis on the practical applicability of the presented knowledge in everyday outpatient psychiatric settings. Therefore, it focuses especially on interventions or educational resources that can be directly offered or recommended to patients, their families, or close ones within time-limited conditions. As an example...

Pharmacokinetic aspects of the second generation long acting injectable antipsychoticsReview articles

MUDr. Martin Hýža, Ph.D., MUDr. Tomáš Skřont

Psychiatr. praxi. 2025;26(3):151-155 | DOI: 10.36290/psy.2025.025

Second generation long acting injectable antipsychotics supply gradually the portfolio of the agents available for the treatment of schizophrenia. The first preparation (risperidon microspheres) has been approved by FDA already in 2003, the last one (aripiprazol monohydrate once in two months) even in the last year. Compared to the first generation their great advantage is in better tolerability and the potential to improve affective symptoms among others. Recently new preparations with longer interval (2 or 3 months) have been introduced. Second generation LAI antipsychotics are characterized with more precisely defined pharmacokinetic profiles and...

The diagnosis and pharmacotherapy of adult ADHD - part 2Review articles

MUDr. Michal Vodička

Psychiatr. praxi. 2025;26(3):143-150 | DOI: 10.36290/psy.2025.024

The second part of the review article on ADHD focuses on the common comorbid disorders that co-occur with ADHD, their differential diagnosis and current pharmacotherapeutic approaches targeting ADHD and individual comorbidities. Furthermore, it addresses the issue of self-injurious and suicidal behaviours in patients with ADHD, along with pharmacological interventions for these conditions.

Pište také pro nás!Editorial

MUDr. Radkin Honzák, CSc.

Psychiatr. praxi. 2025;26(2):67

Léčba hypomagnezemie jako možné příčiny některých symptomů neurologických poruchCommercial presentation

MUDr. Jiří Havel, MSc.

Psychiatr. praxi. 2025;26(2):130-134

Highligths: informace a dojmy z 10. mezinárodního sympozia Světové federace ADHDHeard at a congress

MUDr. Hedvika Ernsten

Psychiatr. praxi. 2025;26(2):127-129

Comorbid anorexia nervosa and obsessive-compulsive disorder in adolescence - a case reportCase report

MUDr. Barbora Pilátová, MUDr. Kryštof Kantor, Ph.D., doc. PhDr. Jana Kocourková

Psychiatr. praxi. 2025;26(2):123-126 | DOI: 10.36290/psy.2025.021

Anorexia nervosa and obsessive-compulsive disorder (OCD) are mental disorders that often develop during adolescence. These conditions share some common features and can occur simultaneously, which can lead to complications in the diagnosis and treatment of both disorders. Adolescence is a specific period of life that is associated with rapid changes in psychological status, even in the absence of pathology. In the case study of an adolescent girl, we highlight the phenomenological overlap in symptomatology between these two comorbid disorders and the fact that correct differentiation of the causes of the observed behaviours can play an important role...