Psychiatr. praxi. 2016;17(3):104-107 | DOI: 10.36290/psy.2016.027
Aripiprazole in the treatment of bipolar disorder - its use in the clinical practice
- Psychiatrická ambulance, Psychiatrie s. r. o., Plzeň
- Psychiatrická klinika 1. LF UK a VFN, Praha
Aripiprazole is atypical antipsychotik (partial agonist of D2 and 5-HT1A and antagonist of 5-HT2A receptors). Aripiprazole is effective in the short and longterm treatment of bipolar affective disorder. We demonstrate on 3 case reports of bipolar patients when is possible to use aripiprazole in the treatment of this disorder.
Keywords: aripiprazole, bipolar affective disorder, efficacy, tollerability, augmentation, atypic antipsychotics
Published: October 26, 2016 Show citation
References
- European Medicines Agency, www.ema.europa.eu. Aripiprazol, poslední revize 21. 04. 2016.
- Meduri M, Gregoraci G, Baglivo V, Balestrieri M, Isola M, Brambilla P. A meta-analysis of efficacy and safety of aripiprazole in adult and pediatric bipolar disorder in randomized controlled trials and observational studies. J Affect Disord 2016; 191: 187-208.
Go to original source... 
Go to PubMed... - Dhillon S. Aripiprazole: a review of its use in the management of mania in adults with bipolar I disorder. Drugs. 2012; 72(1): 133-162. Go to original source... Go to PubMed...
- Brown R, Taylor MJ, Geddes J. Aripiprazole alone or in combination for acute mania. Cochrane Database Syst Rev. 2013; 12: CD005000. Go to original source...
- Fountoulakis KN, Vieta E, Schmidt F. Aripiprazole monotherapy in the treatment of bipolar disorder: a meta-analysis. J Affect Disord. 2011; 133(3): 361-170. Go to original source... Go to PubMed...
- Bak M, Fransen A, Janssen J, van Os J, Drukker M. Almost all antipsychotics result in weight gain: a meta-analysis. PLoS One 2014; 9(4): e94112. Go to original source... Go to PubMed...
- European Medicines Agency, www.ema.europa.eu. Quetiapin.
- Fan KY, Chen WY, Huang MC. Quetiapine-associated leucopenia and thrombocytopenia: a case report. BMC Psychiatry 2015; 7(15): 110. Go to original source...
- Rahman A, Mican LM, Fischer C, Campbell AH. Evaluating the incidence of leukopenia and neutropenia with valproate, quetiapine, or the combination in children and adolescents. Ann Pharmacother 2009; 43(5): 822-830. Go to original source... Go to PubMed...
- Park HJ, Kim JY. Incidence of Neutropenia With Valproate and Quetiapine Combination Treatment in Subjects With Acquired Brain Injuries. Arch Phys Med Rehabil 2016; 97(2): 183-188. Go to original source...
- Meng M, Li W, Zhang S, Wang H, Sheng J, Wang J, Li C. Using aripiprazole to reduce antipsychotic-induced hyperprolactinemia: meta-analysis of currently available randomized controlled trials. Shanghai Arch Psychiatry 2015; 27(1): 4-17.