Jak se vede českému lázeňství?

MUDr. Eduard Bláha

Psychiatr. praxi. 2014;15(3):95  

Circadian rhytms in patients with bipolar disorder

MUDr.Dana Kamarádová, Ph.D., doc.MUDr.Klára Látalová, Ph.D., prof.MUDr.Ján Praško, CSc.

Psychiatr. praxi. 2014;15(3):99-102  

Bipolar disorder is linked to circadian rhythms disturbance. However, the exact mechanism underlying the association between circadian rhythm and mood remains unknown. The master circadian pacemaker is located in suprachiasmatic nucleus in hypothalamus. The inner clocks are regulated by cyclic environmental factors. Persons with bipolar disorder may have problems with this environmental synchronization. The discovery of clock genes generating oscillations in gene expression meant revolution in understanding to circadian rhythms. Studies proved that some clock genes variants may play important role in a vulnerability to bipolar disorder. Circadian...

Treatment of insomnia in children with ADHD

prof.MUDr.Ivana Drtílková, CSc.

Psychiatr. praxi. 2014;15(3):103-105  

Summary. Behavioral interventions should be considered as first-line treatment of insomnia, although further evidence from randomized controlled trials (RCTs) is needed to prove efficacy in ADHD. Among pharmacological treatments RCTs support the use of melatonin to reduce sleep-onset delay in ADHD. There is more limited evidence for efficacy other medications.

Dual-action antidepressants - the use in clinical practice

doc.MUDr.Martin Bareš, Ph.D.

Psychiatr. praxi. 2014;15(3):108-111  

Dual-action antidepressants (duloxetine, mirtazapine, venlafaxine) are widely used in clinical practice. The author comments and compare their mutual efficacy in the treatment of major depression, tolerability, use in other indications and in the treatment of special populations (depression in old age, pregnancy, breast-feeding).

Diagnosis and pharmacotherapy of adult ADHD

doc.MUDr.Jiří Masopust, Ph.D., doc.MUDr.Pavel Mohr, Ph.D., doc.MUDr.Martin Anders, Ph.D., prof.MUDr.Radovan Přikryl, Ph.D.

Psychiatr. praxi. 2014;15(3):112-117  

Attention deficit and/or hyperactivity disorder (ADHD) is among the most common psychiatric disorders of childhood that persist into adulthood in the majority of cases. Diagnosis of ADHD should be considered even if not diagnosed earlier during childhood; persistence of symptoms and fuctional impairment are essential. Stimulants and atomoxetine are the drugs with the strongest evidence of efficacy in therapy of adult ADHD. Atomoxetine is the only drug approved for treatment of adult ADHD in the Czech Republic. This paper summarizes data on diagnosis and psychopharmacotherapy of adult ADHD.

Cognitive behavioral therapy of chronic hallucinations

MUDr.Kristýna Vrbová, prof.MUDr.Ján Praško, CSc., Mgr.Marie Ocisková, Mgr.Lucie Šmejkalová

Psychiatr. praxi. 2014;15(3):117-124  

The lifetime prevalence of schizophrenia varies according to epidemiological studies between 1–1.5 %. Although modern pharmacotherapy led to a significant reduction of patient’s suffering, about 25 % of schizophrenic patients are described as “pharmacologically resistant” and 20–60 % stop taking recommended medication. Except the symptoms that are resistant to the treatment, progression of the disease is negatively influenced by other factors, such as premorbid personality, cognitive deficit, family and interpersonal problems, drug and alcohol abuse, stigmatization. All these factors are pointing to the need to...

Prion dementia

MUDr.Richard Krombholz

Psychiatr. praxi. 2014;15(3):125-128  

Prion diseases are very rare cause of the syndrom of dementia, their incidence is 1–2 cases per 1 million populations per year, which means about 1 per mille incidence of Alzheimer‘s disease. But this is a serious disease with a long incubation period and life limiting prognosis. The psychiatrist may be a doctor of the first line, who comes into contact with the patient. Important for the first expression of the suspicion of the prion diseases is the knowledge of the clinical image and the differences from the more commonly occurring dementia. For clinical practice, it is also important to know the epidemiological measures related...

Alcohol and drugs in the driving of a motor vehicle and assessment of fitness to drive

MUDr.Jiří Švarc, Ph.D.

Psychiatr. praxi. 2014;15(3):129-133  

If the serum level of alcohol in a driver of a motor vehicle (MV) exceeds 1 g/kg, the driver is prosecuted for the misdemeanour of threat under the influence of addictive substance according to Article 274 of the Penal Code. Similarly, until recently, a driver has been prosecuted if any amount of a drug (most commonly THC or methamphetamine) was detected in the serum. In nonalcoholic addictive substances, however, cut-off levels similar to those in alcohol have been advocated, i. e. 1. a cut-off level below which a driver is not considered to be under the influence (0.2 g/kg for alcohol); 2. a cut-off level above which fitness to drive is...

Autentičtí pokračovatelé Schultzova autogenního tréninku v ČR

Mgr. et Mgr. Veronika Víchová

Psychiatr. praxi. 2014;15(3):134