Psychiatr. praxi. 2023;24(1):8-12 [Klin Farmakol Farm. 2022;36(4):150-155]

Reinitiation of clozapine treatment

MUDr. Michaela Mayerová, Ph.D.1, prof. MUDr. Libor Ustohal, Ph.D.1, 2
1 Psychiatrická klinika, Fakultní nemocnice Brno a Lékařská fakulta Masarykovy univerzity, Brno
2 Ústav farmakologie a toxikologie, Farmaceutická fakulta Masarykovy univerzity, Brno

The article deals with the reinitiation of clozapine treatment after it was discontinued for a reason (mostly because of side effects). Reinitiation is a controversial topic, especially after severe to life-threatening side effects. When is the reiniation possible and how should this be done? We try to provide a summary of relevant information which is available in literature of recent years or in therapeutic guidelines.

Keywords: clozapine, reinitiation, side effects, myocarditis, agranulocytosis, ileus, schizophrenia.

Published: April 11, 2023  Show citation

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Mayerová M, Ustohal L. Reinitiation of clozapine treatment. Psychiatr. praxi. 2023;24(1):8-12.
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