Psychiatr. praxi 2017; 18(2e) [Onkologie. 2017:11(1):29-33]

Rational use of psychotropic drugs in oncology – selected indications, interactions, tips for practice

Jana Gregorová^{1, 2}, Petra Holečková^{3, 4}

¹ Oddělení klinické farmacie, Nemocnice Na Bulovce, Praha

² Ústav aplikované farmacie, Farmaceutická fakulta VFU, Brno

³ Ústav radiační onkologie, Nemocnice Na Bulovce, Praha

⁴ 1. lékařská fakulta UK, Praha

Indications psychotropic drugs in oncology include also chemotherapy-induced neuropathy, delirium, nausea, emesis and affect appetite. Psychotropicdrugs are often used "off label" and should be used in patients to attention. Levels of some of psychotropic drugs may be affected by a number of concomitantly administered drugs due to pharmacokinetic drug interactions. Dexamethasone, phenytoin, and carbamazepineare often the co-medication with the above-mentioned indications, among the important enzyme inducers and may reduce the effect ofpsychotropic drugs. Combinations of psychotropics potentially increased risk of pharmacodynamic drug interactions.

Keywords: psychotropic drugs, onkology, drug interaction

Published: July 1, 2017  Show citation