1136
PSYCHIATRIE341804001074588136186244265319357405427470
PRO833804001074591153
PRAXI1008804001074591148201221
/12758040010731
Psychiatr.1351804001074578119159207225266293320332
praxi.1703804001074976118158177193
2025;26(2):116-1221916804001074386128172185229271295338360374412446485515553591635
/25968040010731
www.psychiatriepropraxi.cz46148040010765133201214264298339379427445485513539559602652679726776803845884904919960998
1221318020012657110167
PSYCHOFARMAKOLOGICKÝ341200012660119184242315391449515579669739806879935100910811116117912461314
PROFIL1677200012660124199256289345
Změna34136001063185117158198
farmakokinetiky55536001062867102157197233272307325366398432449485524
vybraných109536001063675111147189230267300341
psychofarmak145236001063266103136177218249287322377417453
u1921360010638
pacientů197536001063370103120152194226267
s2258360010630
chronickým230436001063374109150192209244279318372
onemocněním269236001063880111166206242283315356374428
ledvin313536001062962101139156197
Buspiron480610011053107147202227260314368
se87462001073480
významně98262001074287127178221297347392
metabolizuje1402620010776122151194246297317337375425445491
na192162001074991
jeden34076001071962111154201
méně557760010773116164207
účinný78076001074786104151198236
metabolit1032760010773116143184232280300317345
a1393760010740
více14497600107405998139
neaktivních160476001074891131168198216256304322361409
metabolitů.340900010773116143184232280300317345391406
Většina76190001074687114148166213252
buspironu102990001074997129177195221267315361
je140690001071962
vyloučena148490001074082101149196235277324364
močí1864900010772120340104001074058
ve415104001074184
formě51610400107237197172216
metabolitů,7481040010774118146187237286305324352399415
které1179104001073869112138181
se1377104001073377
u14711040010748
renální1535104001072770118158177225243
insuficience179510400107196799146170190340118001074059103151191234
kumulují592118001073886159207226273292311
(44).921118001072365112133146
U10851180010757
pacientů1160118001074991131150194242269317
s14951180010733
CrCl1546118001075178131149
<17131180010754
501785118001074487
ml/1887118001077493125
min340132001077492140
je501132001072064
vhodné586132001074089138188236280
zahájit887132001073779127168187205233
podávání1142132001074998148189229270319337
s15001320010734
nižší1555132001074867103139157
dávkou,1733132001074990130168216264279
např.340146001074991142170181
5–10549146001074492132173
mg7381460010776127
dvakrát892146001075093135175204247275
denně1194146001075096145195240
(22).1462146001072468113137150
Vzhledem1640146001074785135155200251297372
k3401600010738
vyšší393160001074083116148165
expozici574160001074382131179214232272289
aktivnímu879160001074078108126166214232304350
metabolitu12451600010773116143183232280299317344391
buspironu1652160001074996128176195220266314360
je340174001071962
u4171740010748
anurických480174001074087134159178217254296335382
pacientů877174001074990130147190237263310
doporučeno1203174001074895144192218266305346394441
redukovat1660174001072668117163200246285326352
dávku340188001074990129168216
na580188001074889
50–75693188001074487135175216
%.933188001076683
(45).1040188001072466107130143
Buspiron1207188001074593126175195221268317
není1547188001074993141159
dialyzovatelný1730188001074968108127167206253340202001074182109152171219257
(46).617202001072465111134147
Gabapentin4802150011061107160206259307359390413464
a9682160010741
pregabalin1034216001075077120169210259300319337384
se1443216001073478
vyznačují1546216001074184123171212252299318335
zanedbatelným1906216001073779340230001074892141189230256298316363401474
metabolismem8352300010774117144185233282300318350422465538
a13942300010741
významným1455230001074183121169209282329366440
renálním1916230001072668340244001074888106153171243
vylučováním608244001074083102148188233273313361378451
v10832440010741
nezměněné1148244001074992128202245292335382426
podobě.1598244001075098147195244288302
Při192424400107457088
zahájení340258001073678125165183226273291
léčby649258001071962103151190
těmito857258001072870142160187233
léčivy1109258001071962102119160202
u13302580010748
pacientů1396258001075091130148191238264311
s17262580010733
CKD1778258001075295154
je1950258001072063
nutné340272001074895122170213
dávku573272001074989128166213
navyšovat806272001074988127170202250289330356
postupně1182272001075098131159206255302346
a15482720010741
s16092720010734
hodnocením1663272001074896145192240280321340286001074865137
terapeutického49128600107286994134182225272298316355391433480526
efektu1032286001074365107144174220
vyčkat1266286001074182120157197223
až1504286001074076
do1594286001074995
dosažení1704286001074895127167203244291308
předpokládaného340300001075076117167215263301321361409449496539587634
ustáleného994300001074779108148166209256300347395
stavu1408300001073462102141189
ke1616300001073880
kterému1716300001073868110135177250297
dochází214062001074996136182222258276
až243062001074177
výrazně252162001074182109149185232275
později,281162001074997131178221238255269
než309562001074891127
u3236620010748
pacientů329862001074990129147189236261308
s3620620010734
normálními3668620010748951212140760010774114132179197269287
renálními245276001072668116156174221238311329
funkcemi.280576001072472119156195237310327342
Příliš31727600107457088108126157
rychlá335476001072669107155173213
titrace3591760010728467399140180221
může2140900010774120156198
vést235590001074183116144
k2517900010738
rozvoji257390001072672107150196215232
nežádoucích282390001074891128169217265312352369408456
účinků.329690001074887105152189236250
U3564900010756
pacientů3638900010749901301472140104001074491117164
s23231040010733
ESKD2375104001074284127186
se2580104001073377
biologický2676104001074968115133181230248287324366
poločas3061104001075098117164204245277
gabapentinu3357104001074989138178227271318344362409456
prodlužuje2140118001075075121170188235270317335378
přibližně253311800107497593141160177213260303
na2851118001074888
1322954118001074380120
hodin,3088118001074896145162209224
u33261180010748
pregabalinu3389118001074975117166206254295313330377423
pak2140132001074989126
na2280132001074887
482382132001074387
hodin2484132001074794143160207
(47).2705132001072464102125137
Dávku2857132001075897135172219
gabapentinu3090132001074988136176224268314340357404450
je3554132001071961
třeba363013200107275394142182
upravit2140146001074896122163202221248
již240314600107193772
při249014600107507694
poklesu2599146001074998135155198231277
CrCl2891146001075176129146
pod3052146001075098147
803214146001074488
ml/min,3316146001077492123194211258273
u36041460010748
pregabalinu36671460010749751172140160001074990139181199217265312
při247716000107507695
poklesu2597160001075099137157201234281
CrCl2903160001075278131149
pod3077160001075099149
603251160001074489
ml/min.3354160001077493125196214262278
Obě36571600010761111155
léčiva2140174001071962102120160201
jsou235917400107195198145
dialyzovatelná2522174001074967106125164202248287328354396414461501
(48,3041174001072364109124
49).3183174001074384106118
Závěr21401990014768131190251294
Z22802160010750
uvedeného2356216001074991136187232281326376425
přehledu2808216001075178122171190235286335
je3169216001072065
patrné,3260216001075194121148198244258
že3544216001073882
dávkování36522160010750921322140230001073885125166214231
psychofarmak2396230001075083124163211259282324349423464501
u29222300010748
pacientů2995230001075091131149192240266314
s33332300010734
chronickým3392230001074088114160209226266304346420
onemocněním2140244001074999144219269311360405453472547
ledvin2713244001072065116157177226
(CKD)2965244001072475120181203
vyžaduje3194244001074286125168218267286331
pečlivé3551244001075196138157176217261
zvážení2140258001073679120156198245263
farmakokinetických242225800107246591164204241287325344391435462480519556598637684
faktorů3125258001072465102132178204251
konkrétních3396258001073884132169196238265312330369416
léčiv.2140272001071962102120160171
Změny23282720010748121164211249
v25932720010741
clearance2651272001074058101140165206253293335
a30022720010741
vazbě3060272001074081117167211
na3287272001074988
plazmatické3392272001075069108145218258284302341378420
bílkoviny214028600107517091129176217236285324
mohou24902860010775124173222271
významně2787286001074185124174215290338383
ovlivnit3196286001074989109127169218237265
farmakologické3487286001072467931692102482962140300001071966116133173210252
účinky2416300001074787104151188230
těchto2670300001072869110157183228
léčiv2922300001071962102120160
a31063000010741
zvýšit3171300001073679121154171199
riziko33933000010727458199136183
toxicity.359930000107287411112916918639406200107287182
Depotní4047620010759104154203230278296
formy43696200107237198172211
renálně460562001072770118158177225269
eliminovaných48996200107446381155173221269309351399437477525
léčiv544962001071963104122163
(risperidon,3940760010724476597146190215234282329377392
paliperidon)435676001075090108126175219244263311358406426
by480776001075088
měly4919760010774117136175
být511876001075088119
podávány526176001075098147187226267314351
pacientům,394090001075090130148191238264311383398
u4360900010747
kterých442990001073868110135177216263
je471490001071962
dostatečná479890001074996129157197224265305353392
míra521290001077491117158
jistoty,5391900010720376997143169211222
že3940104001073678
jejich40411040010719628097137184
renální4247104001072769116156174221238
funkce4508104001072371119156194236
jsou476610400107195199146
stabilní.4934104001073462102151169187234252267
U52231040010756
pacientů5302104001074990130147190238264310
podstupujících3940118001074996144176203249296343360377415432471517
eliminační447111800107436077148165211250289335352
metody,48371180010772115141186234272282
jako513311800107195894139
je5286118001071961
dialýza,5361118001074866104121160197237251
je3940132001071962
navíc4022132001074888126145184
důležité4225132001074996114157193211238280
brát4524132001075076117143
v46861320010741
úvahu4746132001074888129176223
míru4988132001077491117164
dialyzovatelnosti51721320010749671061241632012472873273533954133940146001074999132162181
jednotlivých4146146001072065115164213241260278320364404453
léčiv,4624146001072065106125166177
což4827146001074188124
závisí4977146001073780120140173191
na5194146001074991
vaznosti5310146001074284122171220254284303
na3940160001074888
plazmatické4051160001075068108144218258284302341378420
bílkoviny,449416000107506888125171210229276314324
velikosti4841160001074183101119156202235263281
distribučního514516000107496698126152171219267306353371420467
objemu3940174001074795113155227272
a42261740010741
dalších4281174001074887104135152190236
vlastnostech.453117400107405997129156203249281309349389435450
Vzhledem4995174001074580127144186234277348
k53571740010738
tomu,5409174001072772144189203
že3940188001073678
psychiatrické4040188001075082122161208226265292317336375412454
komorbidity,4516188001073884158205231281299347365392434444
jako498218800107195996142
jsou514618800107195199146
deprese,5314188001074992141167209241285298
úzkost3940202001074987126175209238
a42042020010742
delirium4273202001075095114133160179228303
jsou4602202001072053103152
u47802020010749
pacientů4856202001075193135153198247275324
s52062020010734
CKD5266202001075398159
relativně545220200107277190132394021600107284687135179
časté,4143216001074181114142184198
je4366216001071962
nezbytné4453216001074992129179217248296340
sledovat481721600107345295145193232273300
jejich51422160010719628098138185
klinický535221600107385876123141181218260
stav3940230001073462102141
a40982300010741
provádět4157230001074975122161202250293320
případné449423000107507694143183232279322
úpravy4834230001074896122163202244
dávkování,5096230001074988127165211251291339356371
aby5484230001074190128
bylo3940244001075088107154
dosaženo4118244001074997129170207248296343
optimální4485244001074897124142214254272319337
terapeutické484624400107286995136184228275302320360397439
odpovědi53092440010748971461942332753940258001075069
s40352580010735
minimálním4096258001077695144162238279298347366441
rizikem456325800107284784104142186262
nežádoucích4851258001075095132175226275325366385426475
účinků.5352258001074990109158196246260
Nedostatek39402720010757100148195227255294320361398
informací435227200107196587133159231270310327
o46932720010748
farmakokinetice475527200107236489161201237283320339385428454472511551
a53212720010740
dávkování53762720010748871261632083940286001074181128146
psychofarmak4103286001074982122161208255279320345419459496
v46152860010741
této467228600107287097142
populaci4831286001075098147195213252292310
s51572860010734
sebou5207286001073477126174221
nese5445286001074891124167
potřebu3940300001075098124150192241288
dalšího4246300001074989107138156205252
výzkumu4516300001074183121159206279325
v48593000010741
této491830000107286996142
oblasti.5078300001074897116155188216234249
LITERATURA341323001234978134189250318368438498567
1.34034000853649
Cohen40934000834077116152190
SD,6203400083327889
Norris72934000834584106128143170
L,91934000833246
Acquaviva98534000834173111149182214230262296
KA,13013400083358094
et141634000833456
al.14933400083324861
Screening,15743400083336687121157195211249288301
Diagnosis,1896340008345619334035000833876114141156182195
and55635000833169109
Treatment6853500083325084116137196231269290
of99635000833756
Depression107335000834580120141175202229244282320
in141435000831452
Patients14873500083356788104138176198226
with17333500083516689127
End-188035000833371110132
-Stage3403600083215273106145180
Renal54136000833570108141156
Disease.7183600083456187122154180215228
Clinical9663600083405570108123155188204
Journal119036000832463101122161193208
of141936000833756
The149636000833372107
American162336000834199135156171204236275
Society1918360008332713403700083324884108143
of50537000833858
Nephrology.58537000834682123163185224241281322355366
2007;2(6):1332-1342.97337000833570108142153189207242261274305336371404426458489526560573
Available156837000834274109125141174215232268
from:18583700083194281141154
doi:10.2215/CJN.03951106.3403800083387692104134165178214248280310334373400445458493527560594625653684720733
2.34039000853650
Al40639000834155
Farsi4773900083326080106119
RS,6123900083356879
Al70739000834155
Alawi7783900083415585135149
AM,94339000834195107
Al106639000834155
Huraizi113639000834581101132146174188
AR,13403900083417588
et144339000833455
al.15143900083324657
Delirium15873900083457993107127141177233
in183639000831551
Medically1903390008354883404000083385282114128142172
Hospitalized52740000834481106143158179210224238265298336
Patients:8784000083356586100133170190216227
Prevalence,11204000083355487118149163197233264296307
Recognition144240000833569100135173210224245259295332
and178940000833268106
Risk19104000083354974102
Factors:3404100083325989111146165191201
A550410008341
Prospective6004100083355388113150183213235249279311
Cohort92141000833974110146165188
Study.11184100083325187124154162
Journal12894100083246096115151181195
of149341000833754
Clinical15564100083405366102115145175189
Medicine.175441000835486124137167180215248258
2023;12(12).3404200083346596128138166193208238265281290
Available6394200083416999113126156192206239
from:8874200083183873128138
https://10354200083375678115140150175193
doi.org/10.3390/jcm12123897.1237420008338738798133153189213243272283316347378411433447477532560587617644677709741771775
3.34043000853650
Bitan4034300083355072104142
DT,5574300083457685
Krieger6544300083355772106145179200
I,86743000831427
Berkovitch9064300083357090120157189204226256294
A,121243000834154
et127943000833355
al.13474300083314659
Chronic14184300083407798134172187218
kidney16494300083294583121155186
disease1847430008338537811314434044000832660
in41244000831552
adults47644000833170106121143170
with6584400083506587125
schizophrenia:7954400083265794109137174213250271304342356387399
A1206440008341
nationwide12594400083376990105142180229244282316
population-based15884400083387611515216719821923427130933137040234045000832661100
study.4534500083264987126158168
General63345000834479117152173206221
Hospital86745000834482109147163185218233
Psychiatry.11134500083356193125163178209231252286296
2019;58:1-6.142245000833468100130142177211223253272309322
Available175745000834171104119134166205221255
from3404600083184078136
doi:10.1016/J.GENHOSPPSYCH.2019.4914600083387792104134165178209240272303328349361405438483528576608643678711747785830843879913945975986
01.14924600083356676
007.158346000833470103109
4.34047000853651
Tzeng4084700083335792130169
N-S,5934700083456899112
Hsu72147000834571108
YH,8464700083358093
Ho95647000834482
S-Y,1055470008332558796
et116747000833457
al.12404700083324760
Is131747000831541
schizophrenia13744700083275997112141178218256277312350365397
associated178747000833259851231561712033404800083225595
with4544800083516689127
an60048000833270
increased6894800083145284106140172198233273
risk981480008321366292
of109248000833757
chronic11684800083316990127166181213
kidney14004800083304685123158189
disease?16094800083385379114146172207232
A1860480008341
nationwide1920480008338703404900083223775113164179218253
matched-cohort61049000835789111142180215254276310347386424445470
study.10964900083275088127159169
BMJ128149000833590116
Open.141449000834786122160173
2015;5(1).160449000833468100130141176193225239250
Available1871490008341711041193405000083154786102137
from:4925000083194178136148
doi:10.1136/BMJOPEN-2014-006777.6565000083387692104133165177208236266300325362417443491527559604627658692724755778815851887920954989995
5.34051000853651
Tašková4115100083336187117155187220
I.65151000831528
Psychofarmaka7005100083356194125163202221255276334367397431
v1151510008332
kazuistikách.12035100083306393131146173196211241275307345358
Praha:15825100083355689127159172
Maxdorf177451000835587119157195217238
Jesenius;3405200083245986121159174212238250
2021.60552000833569101133142
6.34053000853651
Mohr40453000835492130151
P.56753000833540
Klinická6195300083355166103118149179212
psychofarmakologie.8435300083396597128165203222255276333365395432448485524539573585
Praha:14405300083355688126157169
Maxdorf,162253000835486117155192213234245
2017.18795300083346899128134
7.34054000853644
Ward39754000835788109147
ME,55654000835587100
Musa66954000835492118150
MN,83254000835499112
Bailey957540008335678297132163
LG.11335400083317286
Clinical12325400083405569107122153186201
Pharmacokinetics144654000833572104124182214246283313329367401424439470498
of195654000833756
Lithium.3405500083314567104118155211224
The57555000833270104
Journal6915500083246198118156187202
of90455000833755
Clinical9715500083395468105119150182196
Pharmacology.117955000833571102123179211242278293330368399408
1994;34(4):280285.1599550008334639713214317721123026227829032435639034056000833468102114
Available46956000834172105120135167206222257
from7415600083194178136
doi:10.1002/J.1552-4604.1994.TB01994.8935600083387691104133165177208240276309335356368399429462495515552588623660672703733768804817847884919951981101610521065
8.34057000853653
Seyffart41457000833368100123142176197222
G.65757000834459
Drug73757000834568106146
dosage90457000833877104138178213
in113857000831553
renal12125700083215594127143
insufficiency.13755700083155480118137155173206221257295328362372
Springer17685700083337294110149188224245
Netherlands;34058000834580102140175196212244282322348360
1991.71558000833465100132141
9.34059000853647
Keller397590008334678194127146
F,55359000833236
Maiga5995900083548497134165
M,77359000835466
Neumayer84859000834578113169199228261280
HH,11385900083438697
et124559000833354
al.13085900083324556
Pharmacokinetic137459000833570100120176206237272300315351384404418448
effects18315900083345270103133156181
of34060000833755
altered407600008332466799119152190
plasma6096000083395384109166196
protein8186000083385994115147161197
binding10286000083385289127140177214
of125560000833755
drugs13226000083385895132157
in149160000831551
renal15546000083215490121135
disease.17026000083385176110140165199210
European1924600008332683406100083215897133164202
Journal56061000832563101121160191206
of78561000833856
Drug86061000834667105144
Metabolism102261000835690112145183222237251277335
and137561000833370109
Pharmacokinetics.150361000833573104125183215247284314330367402423438469497509
1984;9(3):275-282.3406200083346397131142176194226242252286318349370399431464475
Available82762000834170102115129160198212246
from:10856200083193975132143
doi:10.1007/BF03189651.1241620008338748899128158169198228263294313348380413444474504537571603633641
10.3406300085356883
Hermida4356300083437898155170208239
J,68663000832435
Tutor7336300083326587123144
JC.8896300083246476
A977630008341
Theoretical103063000833270104142163196217232263295310
Method135263000835488109147184223
for15876300083185475
Normalizing167463000834482103160191206220249264301339
Total3406400083336788121137
Serum4916400083336889127185
Valproic6906400083366783122143180196228
Acid9326400083417388127
Concentration107364000834077115148181219241262295317332370409
in149664000831553
Hypoalbuminemic15636400083447611615518820324228033835339142634065000835771102
Patients.4546500083356687102136173194221234
Journal7006500083246199119157189203
of91665000833655
Pharmacological98365000833571103123181212244280295332371386417449464
Sciences.14596500083326378112149180213239252
2005;97(4):172465000833367102135145180212228260277288
489-493.34066000833470104128165198231243
Available59866000834172105120135167207222257
from:8716600083184077136148
doi:10.1254/JPHS.FPE04007X.10346600083387692104134165178209238273308333354390434466479513548581615651687724756795809
11.3406700085366780
Alshogran4416700083425784123162202224257296
OY,7586700083488291
Nolin87067000834584101116155
TD.10466700083338092
Implications115967000831574114130145178212234250288328354
of153467000833858
Kidney16136700083355292131166199
Disease1833670008346628812415634068000832764
on43068000833979
Metabolic53668000835693116151192233250266300
Reduction.86368000833673115154188214230270311325
Current121568000834179102125161201224
Drug146568000834770111152
Metabolism.164368000835693117151193233251267295355369
2016;17(7):663-672.34069000833469101132145175205222257277289324360395417454488522535
Available89669000834172105120136168208224259
from:11766900083194179137150
doi:10.2174/138920021713476900083387792105135166179216247277308333367397432466500534571604636666
666160603131320.34070000833470105136167202238273307338368398428461495508
12.3407100085366884
Turpeinen4427100083336687127162178215250289
M,74971000835467
Koivuviita8347100083357388121159192208223245278
N,113071000834557
Tolonen12057100083336783121160195233
A,145671000834155
et152971000833456
al.16037100083324760
Effect16817100083335271105138162
of186171000833756
renal1935710008321553407200083387085
impairment44072000831572111144160181239274312334
on78972000833775
the8797200083226095
pharmacokinetics98972000833877109130189221253290321337375410432448480507
of151172000833757
bupropion158272000833977116138175215230268307
and190472000833169108
its3407300083153967
metabolites.42973000835996119153194234251267290325353368
British819730008336587598114142181
Journal102273000832564104126166200216
of126073000833858
Clinical13407300083415773112128162196212
Pharmacology.157473000833675108131191225258297313353394428438
2007;64(2):165-173.34074000833468104137147183219238272290302332363397419450479513526
Available88674000834171104119135167206222257
from:11637400083184078136148
https://doi.org/10.1111/J.13317400083385983123150162189209245283299312350371409436469500513543571599626648669681
1365-2125.2007.02866.X.3407500083346499132154185217247282294330364400432439474507540576611624665679
13.3407600085366883
Parent4407600083356788122160182
X,63976000833851
Marzullo70776000835487108139177192207246
C,96976000834053
Gutlub103976000834482104120157196
AM.125276000834197111
Acide13807600083407287126161
valproïque:15587600083316480118140177193231269304316
estimation189176000833461849934077000835790111127165203
simple5577700083264198137153188
de75977000833873
la84577000831547
concentration90577000833269107139173211233254287309324362400
sérique1319770008326618298137174209
libre.1542770008314296890124136
Annales169277000834179117149165199226
De193277000834580
Biologie3407800083355088103141180195230
Clinique.5827800083405569107122160197232244
1993;51(6):649-650.8387800083346499132143178208223256274285320357389413449483517529
Available138078000834071103118133165204219254
from:16467800083194077135147
https://18067800083375882121148160186207
europepmc.org/article/MED/8172404.21403400083347293130170205244303335348386408446472502524548564596611646672727760805829863895924959990102610631075
14.21403500085366984
Pistolesi2238350008335507699136152187213228
V,248035000833645
Morabito253935000835493114147187202225261
S,281535000833245
Di287435000834561
Mario294935000835487108123161
F,312535000833238
et317735000833456
al.32473500083324760
A3321350008341
Guide33763500083448297136171
to356135000832259
Understanding36343500083448112015521403600083215074108147188203243283
Antimicrobial244536000834281104120179195228251289330347380396
Drug286336000834669108149
Dosing303336000834787115130169210
in326436000831555
Critically33403600083416380103119152186202218251
Ill36133600083153147
Patients3681360008337709210821403700083347294121
on228137000833776
Renal237637000833671109141157
Replacement255237000833671110126158190224282317355376
Therapy.294837000833372107128161200232242
Antimicrobial320937000834179101116174189221242280319335367382
Agents361137000834179114152174201
and214038000833270109
Chemotherapy.226938000834078113171209231269304325358398429439
2019;63(8).272838000833468100130143179213231264283293
Available304238000834171104119135167206222257
from:33193800083184078136148
doi:10.1128/34873800083397792104134166178209237266300325
AAC.00583-19.214039000834184123136171208242276310332363393404
15.21404000085366883
Šefer22424000083326887121142
S,240340000833245
Degoricija246640000834681121159180196228243258290
V.277540000833545
About283840000834181119157180
Drug303740000834567105144
Dialyzability.31994000083466193109140171205244259275289312346356
Acta35734000083417397129
Clinica3721400008340557021404100083385385117
Croatica.22764100083406198131153168200233246
2003;42(3):257-267.254141000833468104137149183216233267284296331366399418449483515522
Available308141000834172105120135167206222257
from:33574100083184077136148
https://hrcak.srce.hr/file/22424.3523410008338598412315016218921024927021404200083316494109136157188222234273294317335352367402428463498529562594606
16.21404300085356883
Nagler223643000834476114129163184
EV,24324300083326977
Webster252243000835689127153176209229
AC,27644300083407891
Vanholder286743000833566103140178193231266286
R,316543000833549
et322643000833455
al.32934300083324759
Antidepressants33644300083417899114152186225246279305331364401422449
for21404400083185678
depression223444000833873112134168195221236274313
in256344000831553
stage26324400083275082122156
3–5280544000833470104
chronic29264400083316990127166181213
kidney31564400083294684122157189
disease:33624400083385379114146172207220
a3598440008332
systematic36474400083265885109142214045000835790111127159
review23174500083205487102137188
of252345000833757
pharmacokinetics,259745000833978110131189222254291322338376411433448480508521
efficacy3136450008334527088120153185219
and337245000833270109
safety34994500083265978113135169
with36864500083506688126
recommendations21404600083215587124183240275314353385407422460498525
by268446000833870
European27734600083326990127167203234272
Renal306546000833570108140156
Best32404600083357097120
Practice33794600083365689121145161193226
(ERBP).36254600083185186123159176187
Nephrology214047000834580119157179216232270309341
Dialysis24984700083466193109140167182208
Transplantation.27234700083335083121147186202234272294327348364402440453
2012;27(10):3736-3745.319347000833468100130143178210227259290308320355388422456480512544575607619
Available214048000834171104120135167206222257
from:24124800083194178136148
doi:10.1093/NDT/GFS295.25764800083387691104133165177208240275308332378424456477520553585618652687699
17.21404900085377181
Khan225649000833678113153
AN,244349000834391105
Bernardini25834900083367497138173196237254294311
J,292849000832539
Johnston300149000832566107148176202241282
JR,33184900083246379
et343149000833559
al.35254900083325064
Hypokalemia36244900083457912216321405000083306886125187206241
in243350000831557
peritoneal254250000834079104122148189231270306324
dialysis29185000083395893112148178196226
patients.319650000833976101120158200225257273
Peritoneal35215000083367398117143184226265214051000833350
Dialysis22185100083476498115148177193221
International.24685100083155578114137178212235252292333367384398
1996;16(6):652.289551000833567104142155187221241276296309347382418431
Available335551000834275110126143177218236273
from:36565100083194382143157
doi:10.1177/089686089601600628.21405200083387692104134165178208236265300320354389423459494530565601635670706738769804841876910943957
18.21405300085367086
FDA.224753000833378119134
Venlafaxine240153000833670108124157176210242258296332
Extended27545300083336690125163203238278
Release30535300083367187123155182218
Tablets329153000833362102118153176204
-3516530008321
Label355853000833165105141157
information37365300083155321405400083195779138170193208247286
[online].24465400083195695110126164199217229
Available269654000834172105121136169209225260
from:29775400083194179138150
https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020699s107lbl.pdf3148540008338608412415116419121226431837238341745048151554256960964221405500083225468871261581712102482803043393603994384644975195405786116486887267597868128298619009369519771012104610781107112711611194122812631297133313601390142114541469150815231536157616161635
19.21405600085366982
SÚKL.224056000833276111144158
SPC241656000833367108
Argofan.254256000834163101139158192230243
[online].28035600083195593109124161196214225
Available304756000834171104119135167206222257
from:33225600083184078136148
https://mediately.co/cz/drugs/7wXInURKsdljEzWnbVthn7xCVqA/argofan-753488560008338598412315016218921026630121405700083385385106140155186196228265289318348376411432470509535560596646682697734778814849878917932947980101010681105114411781201123912771309133913801418145414951522155315741611164921405800083185290112143176
mg-tableta-s-prodlouzenym-uvolnovanim.2328580008358971191411742132292642873193423693904304514895285435826206496837217528108338729049429589961034106610991137115212101223
20.21405900085377590
Eyler22525900083346683119142
RF,24155900083377278
Unruh251559000834584106146186
M,272359000835670
Quinn281559000834888104143183
DK,30205900083468499
et314159000833558
al.32215900083334963
Psychotherapeutic3306590008336639713017021023327230933136640644348321406000083223870
Agents223260000834180116155177205
in245860000831554
End-Stage253360000833372112135167188222262297
Renal285260000833571110143159
Disease.30326000083466289125157184220233
Seminars328660000833369128143182215237265
in357260000831553
Dialysis.364760000834662941101432140610008326416781
2015;28(4):417-426.223661000833468100130141176209229261279291325356385403440473506520
Available277161000834171104119135167206222257
from:30436100083184178136148
doi:10.1111/SDI.12370.32076100083387691103133165177208236263291313346391406420450480515547580593
21.21406200085367082
Timmer223862000833349107165200221
CJ,24756200083406779
Ad256962000834180
Sitsen2664620008333487098133171
JM,28516200083247992
Delbressine29596200083458196135157191218244259297332
LPC.330762000833167107121
Clinical34436200083405570108123155188204
pharmacokinetics366262000833977110131214063000835992125163195212251287310326359387
of254863000833858
mirtazapine.26286300083587496121155186220260277316352364
Clinical30146300083405672111126159193209
Pharmacokinectics.324563000833574107129189222256294325342381417451476492525553567
2000;38(6):461-474.214064000833569106143156192227246280299311346383414433470503534547
Available270864000834172106122137170210226262
from:29916400083184179138151
doi:10.2165/00003088200038060-00001.31636400083387793105136168181218250281316340375411448485519554590626214065000833468104140174208243279315338376412448484516525
22.21406600085367288
Taylor22466600083336191107145167
DM.2430660008346101115
The256266000833272107
Maudsley268666000835487124164190205240271
Prescribing29756600083355589116149170185225240278317
Guidelines33096600083448297136171187201239274301
in362766000831553
Psychiatry.3697660008335629421406700083316984116138159193204
14th235967000833465242467000491335
edition.24756700083347389111126164203216
2021.270667000833569101133142
23.21406800085367287
Lancaster224368000833165103135168194218251273
SG,25306800083337791
Gonzales263668000834382121150183199234260
JP.29116800083256066
Dothiepin.299168000834684106144160194233249287300
Drugs.330668000834567105144171184
198935056800083346499134
[cited3654680008318486386120159
2024Dec.23];38(1):123-147.21406900083346799131176210242255290324341353387421439470484496525554588610640670702708
Available286069000834070102117132163202217251
from:31246900083184076133145
http://link.springer.32816900083375882121133159179195209246276290317355376391428467501522531
com/10.2165/00003495-198938010-00005.2140700008331681261521862172302662973283623864204564925285615976306646867177477828168498839199509821006104310791115115111851197
24.21407100085377491
Kim225571000833554114
D-K.239371000834772111129
Mid-254671000835572114138
and270871000833273114
Late-Life28467100083326892128153189206227264
Chronic313471000834181104144185202236
Kidney33947100083355495136173207
Disease36257100083466392129163214072000832663
Is222172000831442
Associated22817200083417098138172189222245280321
with26207200083516892131
Parkinson’s27707200083356890122140180207247287300327
Disease,31157200083456290126159187224237
Not337072000834584108
with34967200083506791131
an364572000833271
Increased37347200083155521407300083315489123151187228
Risk23877300083355279111
of251673000833858
Alzheimer’s25937300083415888128165181240277299315342
Disease.29537300083466390127160188224238
Journal320973000832564104126166200217
of344573000833758
Personalized35217300083357093122161201235252268214074000832864105
Medicine.226274000835591132149182199238274288
2024;14(6):597.256874000833469104137150182214235269289302339373407415
Available300074000834173107124141174215232268
from:32867400083184281140154
doi:10.3390/34587400083387794108139172186222257291329354
jpm14060597.214075000831556115146179216253290326359394401
25.21407600085367489
Rosenzweig225076000833675102138177207261296312351
P,262276000833641
Canal268476000834074113146161
M,286676000835669
Patat29567600083366991124147
A,312476000834156
et320176000833457
al.32797600083324861
A3361760008342
review34247600083215689105140192
of363776000833858
the37167600083226196
pharmacokinetics,214077000833978111133193226258296327344383419441457490518531
tolerability26937700083215975111133166206222238253276311
and302577000833271111
pharmacodynamics315777000833978111133192225258296336369408441500516548577
of375577000833757
amisulpride214078000833290105131168184223244260299334
in249578000831452
healthy256878000833772104120142180211
volunteers.27997800083327086123161183217252274301315
Human313478000834482140172211
Psychopharmacology-clinical3365780008335619412616420224228031333439342539403400083316985123163196218252267282321336368401417
and437834000833270109
Experimental.450834000833366106141163179237272311332366381394
2002;17(1):1-13.492334000833469105138151181211228260274286316335366397409
Available535334000834172105121136169208224259
from:39403500083184078136148
doi:10.1002/HUP.320.41043500083387691103133165177208239275308335380425460465501533567580
26.39403600085367187
Canal404336000834073111143158
M,421836000835468
Macmahon430236000835487119177209247286324
M,464236000835568
Kwan472636000833585118156
J,489836000832436
et495036000833456
al.50233600083314760
Amisulpride:509936000834199114140177193231253269308342355
kinetics547036000833046841193940370008322377098
in405837000831553
patients41323700083397294110145183205233
with43863700083516689128
renal45343700083215694127142
failure.4697370008318526783121142177189
European49073700083326991128168204236275
Neuropsychopharmacology.520237000834581119140178218245278310348387394038000833977109131189221254291306345384416426
2000;10(10):330.438438000833468104140153183215234266297316328363396430443
Available484438000834172105120135167207222257
from:51193800083184078136148
doi:10.1016/52843800083397792104134166178209240272303328
S0924-977X(00)80404-6.394039000833267103136168191225258293332349383419438472508544580616639676689
27.39404000085367281
SÚKL.404240000833377113146160
SPC422340000833368109
Amisulprid4353400008342100116142180196235257273313
Viatris.46874000083365285107129145171185
[Internet]4893400008319357495130151191226249267
Available518040000834273106122137170210226261
from:54624000083194179138151
https://mediately.co/cz/drugs/Q48zJesoL0PEjjirLqMe8o6C4WW/amisulprid-viatris-2003940410008339618712815616919721927731335537140442746247851252255659462065068271174977181185187990695499110291059108811241152119212261261129913331349136613821404143814781535157116081648394042000833475108165226248278336351378415430469491506545567600616648670691707733754785819855
mg-tableta.480742000835796119141174213229264286319332
28.39404300085367187
Ashley404043000834168105121155186
C,423943000833952
Dunleavy430343000834583121136170202233267
A.458243000834155
The465043000833271105
Renal476843000833570107139154
Drug493543000834566104142
Handbook.509043000834476113152190229267297312
The541443000833271106
Ultimate55324300083445939404400083223795127149182
Prescribing41394400083355690117149170186225240278317
Guide44734400083438297136170
for46604400083185677
Renal475444000833570108141156
Practitioners.49274400083355588120145160182198236274309330358371
5th5315440008334534844000491335
Edition.53994400083337186108124162200213
CRC394045000834075116
Press40724500083355589116143
Taylor42304500083336191107146167
&4409450008340
Francis44614500083325285123155170196
Group;467345000834365102140179192
2019.488045000833468100130141
29.39404600085367387
Caley40484600083417490126158
ChF,422746000834079113119
Weber436746000835892132169191
SS.45794600083336679
Sulpiride:46794600083337187127143165181221256269
an496946000833271
Antipsychotic506146000834281103119159186219252290330352368400
with54834600083516790129
Selective39404700083337088124159185201236272
Dopaminergic424047000834788130164225242282318341382398432
Antagonist470047000834283106141182222263279307332
Properties.50604700083365898139177200226243279308323
Annals541147000834283123157174201
of394048000833859
Pharmacotherapy.402448000833675109131192226260299322362399421456497530541
1995;29(2):152-160.459048000833567104140151188224244280299312343375410431464497534548
Available516248000834275109125142176217234270
from:54574800083194282142155
doi:10.1177/106002809502900210.39404900083387692104134165178208236265300320353384420456492525558594629663697730764800836869900932944
30.39405000085357186
SÚKL.403850000833275109141155
SPC420550000833266106
Prosulpin.43235000083355591117154169207222259272
[Internet]4607500008318337192125145183217239256
Available487550000834170103117132163202217251
from:51395000083183976133145
https://mediately.co/cz/drugs/CaaB8ZlOjoVqSp1n9cEE25JUF6y/prosulpin-200529650000833758821201461581852042602943940510008338538410613915518619622726428831734737541043146950753355959863066269773277078583284888592095698810261056109011231155118812201255129013131357138914231454147715141535157215991635165139405200083395492115145180216
mg-tableta.416852000835796119141174213229264286319332
31.39405300085366880
Bressolle40335300083355689116142180195210244
F,429053000833237
Bres43405300083355689116
J,446853000832436
Fauré-Jeantis45165300083326198119153175196231262299321335361
A.489053000834055
Absolute495753000834179106143159196218251
Bioavailability,52215300083355087119150183198213244283298313327349383392
Rate39405400083356890124
of407854000833757
Absorption,414954000834181107146167207229244282321334
and449754000833270109
Dose462154000834584110145
Proportionality47815400083355693133171193218233271309342357372395428
of522454000833756
Sulpiride52955400083337085124140161176215250
in556054000831452
Humans.394055000834482140172210236250
Journal420755000832462100121160192208
of443155000833757
Pharmaceutical450455000833573105126185217249283321343358390423439
Sciences.49595500083336580115153185219246259
1992;81(1):2632.5235550008334649913314518021222725927328532035439405600083346779
Available403556000834071104119134166206222256
from:43075600083184078136148
doi:10.1002/JPS.2600810106.44705600083387792104134165178209240276309336357392425439475508544580615647679710742778791
32.39405700085357085
Gallegos-Villalobos40375700083437590104139177215241261296312327341373387425464502528
A,457757000834054
Ruiz-Criado46435700083357286115136178198213244283320
J,497557000832436
Rodríguez502357000833572111131147184221255284
A,531957000834154
et538557000833456
al.54535700083314658
Severe55245700083326639405800083326687121
Parkinsonism40785800083356788119135173200238276291317375
with44705800083516689127
respiratory46145800083215581120136157190212249270304
failure4935580008319526782120141175
in512758000831553
peritoneal51975800083387495111133170209244275291
dialysis550558000833853853940590008315477488115
patient.40745900083397294109144182203217
Nefrologia.43105900083458099121158174212252267299312
2016;36(6):721-722.464259000833468100131144179213232265283295329363394413444479513526
Available518859000834171104119134167206222257
from:54645900083194178136148
doi:10.1016/J.NEFROE.2017.39406000083387692104134165178208240272303328349361407441473508556589603639673704734740
01.46956000083356676
009.478660000833470106116
33.39406100085367186
Steele40456100083325487123138173
JW,42376100083258393
Faulds43496100083326299115153180
D,454861000834556
Sorkin46236100083337193123140178
EM.482061000833388102
Tiapride.49416100083324981120142158197231244
A5204610008341
review52646100083215587103137189
of547261000833756
its55486100083143764
pharmacodynamic394062000833979112134194227260298339372412445504520553
and451462000833372112
pharmacokinetic464762000833979112134194227260298330347386422445461494
properties,516262000833962100141177199225240276304317
and550162000833271111
therapeutic39406300083226095117150189225263286301334
potential429463000833978100134173194210242258
in457263000831553
geriatric46466300083387394110142164186202234
agitation.49006300083327287110143165180218257270
Drugs519163000834667106145172
&5375630008339
Aging.54276300083418095133172185
1993;3(5):460-478.394064000833567104138150187206241260273309346384409447480515529
Available449264000834274108124140174215232268
from:47826400083194281142155
doi:10.2165/00002512199303050-00007.49596400083397995108140172186223256289324349384422460498532568601632394065000833464100132167200235269303327364400436472505511
34.39406600085367388
SÚKL.404466000833276111144158
SPC421766000833368108
Tiapridal.43416600083324981120142157196229244257
[Online]461366000831965104119134172207224
Available485366000834171104119134167206222257
from:51256600083184178136148
https://mediately.co/cz/drugs/TGXHSh7ZcFCTrRULgsok9kLFQHk/tiapridal-10052896600083375983123149162189209265300394067000833854861091431591912012342712973263573854224434825225485746126556957407728118448829149479881024104110781123115511941221125912911327135813921425147315191549157916011617164939406800083396076115147162185215247283
mg-tableta.423568000835897119141174213229264286319332
35.39406900085377388
UpToDate.404969000834585115150198231253288301
Risperidone:43716900083365279119156178194234273313349362
Drug475469000834669108148
information.[online]49236900083155474113135195228251267306345359378416455471487526562580
[cited55246900083195065394070000832258100
2024Dec.23].406970000833571106140188226260275313350369382
Available448070000834275110126143177218236273
from:47827000083194382143157
https://www.uptodate.com/contents/risperidone-drug-information?search=-49687000083386188129158172200222276332388400440481505544586620394071000832257701031422022292592973373593954344574855125335495766176546766927327728128488939179599811021106110841101114111601199122212821316133913551394143414601486152215551577161016491672
risperidone39407200083213968110149173191233274316354
&4310720008340
source=panel_search_result436772000832768109133167204250293329371409427466497535570594628669709735772801842859884
&5268720008340
selectedTitle=1%7E112532572000832765831201561832202623940730008333507288123167198246279311343371401
&4354730008339
usage_type=panel44057300083386498137172209232266306342385426459497532548
&4966730008339
kp_tab=drug_general50177300083307110712916320224628730834738642446349853757239407400083215469
&4021740008339
display_rank=1.40737400083385379118134166197230253286324354395426435
Další46887660011061108131169193
literatura489976600110244779125158204236287320366
u52847660011051
autora5354766001104597129179212258
a43267760011046
na4390776001105298
www.psychiatriepropraxi.cz450777600110671372082272813193654054574805265585906146617147477988518849309761000102210631106